IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain

Print ISSN: 2581-5210

Online ISSN: 2581-5229

CODEN : IIJAAL

IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain (IJASHNB) open access, peer-reviewed quarterly journal publishing since 2015 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing more...

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Original Article


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25-32


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Asmita Nene*, Jenifer Rodriguez Santoni


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Intranasal insulin therapy in the treatment of alzheimer’s disease – A narrative review


Original Article

Author Details : Asmita Nene*, Jenifer Rodriguez Santoni

Volume : 9, Issue : 1, Year : 2023

Article Page : 25-32

https://doi.org/10.18231/j.ijashnb.2023.006



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Abstract

The administration of intranasal insulin improves symptoms related to Alzheimer’s disease. The research was conducted through a hypothesis-based review, such as, PubMed, DynaMed, and EBSCOhost. The articles published between 2011 and 2020 were included. The studies included randomized controlled trials and cohort studies. The study populations included participants associated with cognitive-related conditions. The group of humans and animal models were also considered. All ten articles showed how the administration of intranasal insulin can improve the symptoms related to Alzheimer’s disease. However, these findings varied on the level of dose used, the duration of the treatment and the type of insulin formulations used. Future studies can consider to provide a more homogenous group of study population, cognitive-related activities to observe, and duration of the administration in order to provide a more credible result.


Keywords: Intranasal insulin, Insulin signaling, Alzheimer's disease, Dementia, Cognitive impairment


How to cite : Nene A, Santoni J R, Intranasal insulin therapy in the treatment of alzheimer’s disease – A narrative review. IP Indian J Anat Surg Head Neck Brain 2023;9(1):25-32

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